Wow, I'll keep my opinion to myself, since the only drugs (besides alcohol) that I've ever done, have been perscription ones.
As for those, like mentioned above, most people react differently to any sort of chemical "inhancing" agent: ie- any altering substance, be it tylenol, or crack, and anything in between.
Some people on anti-depressants, for instance, get hornier, while other's have a decrease in libido. Some don't alter at all. Still other's might be just as horny as before, if not more so, but have the inability to orgasm.
Asking for advice on how a drug might affect your sex life is the same as asking if you'll have an easy labor or a hard one. It depends on the person's chemical makeup, not on how other people react to it.