I have a very small family. Mom was an only child, dad only had one brother, and he's got two kids in their early 20s. There is one girl, and she and my brother have hit it off (they live quite far from us, but I know they've online chatted some), but I don't suspect any funny business. Just doesn't seem like it'd be in either of their natures. And me? No not me either.
I don't know any second cousins or more distant relations any better, living up north we've been pretty isolated from most of the family in AR/OK.